the big questions

We are interested in links between transcription and splicing as well as the role of cellular sub-compartments in RNA biogenesis. Our major tools include next generation sequencing and imaging techniques that capture RNA-protein interactions. We study these phenomena in fission and budding yeast, mammalian tissue culture cells, zebrafish, and green algae.

News Highlights

20 March 2026 - The DoGs Group’s paper on imatinib-induced transcriptional readthrough and alternative splicing programs in chronic myeloid leukemia cells was published in Science Advances. Click here to check it out!

27 February 2026 - The Folding Group’s methods paper on Co-transcriptional Structure Tracking sequencing (CoSTseq) was published in JoVE. Click here to check it out!

16 January 2026 - Congratulations to Lokha for receiving the American Heart Association Postdoctoral Fellowship!

5 January 2026 - Farewell to Jackson; we wish you the best of luck as a postdoctoral associate with Don Fox at Duke University!

15 December 2025 - Congratulations to Audry for passing her qualifying exam!

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