the big questions

We are interested in links between transcription and splicing as well as the role of cellular sub-compartments in RNA biogenesis. Our major tools include next generation sequencing and imaging techniques that capture RNA-protein interactions. We study these phenomena in fission and budding yeast, mammalian tissue culture cells, zebrafish, and green algae.

News Highlights

28 April 2026 - Congratulations to Kyle for winning the Sigler Prize for undergraduates!

28 April 2026 - Congratulations to Jae-Hee and Kyle for defending their BS/MS theses!

27 March 2026 - Karla, Guishi, and Audry were featured in an article for Nature Methods on bridging molecular and planetary sciences. Click here to check it out or here for coverage by the MB&B department.

20 March 2026 - The DoGs Group’s paper on imatinib-induced transcriptional readthrough and alternative splicing programs in chronic myeloid leukemia cells was published in Science Advances. Click here to check it out!

27 February 2026 - The Folding Group’s methods paper on Co-transcriptional Structure Tracking sequencing (CoSTseq) was published in JoVE. Click here to check it out!

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