the big questions

We are interested in links between transcription and splicing as well as the role of cellular sub-compartments in RNA biogenesis. Our major tools include next generation sequencing and imaging techniques that capture RNA-protein interactions. We study these phenomena in fission and budding yeast, mammalian tissue culture cells, zebrafish, and green algae.

News Highlights

19 April 2025 - Congratulations to Kyle for being selected as a Joan and Tom Steitz RNA Fellow!

27 March 2025 - Karla was selected as an incoming fellow of the American Association for the Advancement of Science (AAAS). Click here to check out coverage by YaleNews.

25 March 2025 - Leo’s thesis work on nascent RNA structure was published in Molecular Cell. Click here to check it out!

3 March 2025 - Congratulations to Jackson for successfully defending his thesis, “Gene Expression Regulation by PABPN1 Phosphorylation and Microexon Splicing”!

28 February 2025 - Congratulations to Leo for successfully defending his thesis, “Regulation of pre-mRNA Processing Through Nascent RNA Folding”!

Click here for more news.